Guided jaw-bone regeneration using an experimental rabbit model
Identifieur interne : 002337 ( Main/Exploration ); précédent : 002336; suivant : 002338Guided jaw-bone regeneration using an experimental rabbit model
Auteurs : A. K. Lundgren [Suède] ; L. Sennerby [Suède] ; D. Lundgren [Suède]Source :
- International journal of oral and maxillofacial surgery [ 0901-5027 ] ; 1998.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Chirurgie, Biomatériau, Histologie, Analyse quantitative, Lapin.
English descriptors
- KwdEn :
Abstract
The aims of this study were to evaluate the space-maintaining capacity of two biocompatible barrier materials and to assess the effect of barrier occlusiveness on the amount of regenerated bone. Defects were prepared in the edentulous area on both sides of the maxillas in 22 rabbits. The rabbits were divided into three groups. Gore-Tex® augmentation material (GTAM) (ePTFE)-barriers were placed to cover the experimental defects and compared with totally occlusive or perforated titanium foils and uncovered control defects respectively. After four weeks of healing, histological analyses and morphometrical measurements demonstrated that the amount of regenerated bone tissue was about the same underneath the collapsed GTAM-barriers as in the controls. The highest degree of regeneration was obtained in defects underneath the titanium foils, particularly if they were perforated, whether or not they were covered by GTAM-barriers. It was concluded that the space-maintaining properties of a barrier may be at least as important as barrier occlusiveness when regenerating bone defects.
Affiliations:
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Le document en format XML
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K." last="Lundgren">A. K. Lundgren</name><affiliation wicri:level="4"><inist:fA14 i1="01"><s1>Department of Biomaterials/Handicap Research, Institute for Surgical Sciences, Göteborg University</s1><s2>Göteborg</s2><s3>SWE</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>Suède</country><placeName><settlement type="city">Göteborg</settlement><region nuts="1">Götaland</region><region nuts="1">Suède occidentale</region></placeName><orgName type="university">Université de Göteborg</orgName></affiliation></author><author><name sortKey="Sennerby, L" sort="Sennerby, L" uniqKey="Sennerby L" first="L." last="Sennerby">L. 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Lundgren</name><affiliation wicri:level="4"><inist:fA14 i1="01"><s1>Department of Biomaterials/Handicap Research, Institute for Surgical Sciences, Göteborg University</s1><s2>Göteborg</s2><s3>SWE</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>Suède</country><placeName><settlement type="city">Göteborg</settlement><region nuts="1">Götaland</region><region nuts="1">Suède occidentale</region></placeName><orgName type="university">Université de Göteborg</orgName></affiliation><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Periodontology, Institute for Postgraduate Dental Education</s1><s2>Jönköping</s2><s3>SWE</s3><sZ>3 aut.</sZ></inist:fA14><country>Suède</country><wicri:noRegion>Jönköping</wicri:noRegion></affiliation></author></analytic><series><title level="j" type="main">International journal of oral and maxillofacial surgery</title><title level="j" type="abbreviated">Int. j. oral maxillofac. surg.</title><idno type="ISSN">0901-5027</idno><imprint><date when="1998">1998</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">International journal of oral and maxillofacial surgery</title><title level="j" type="abbreviated">Int. j. oral maxillofac. surg.</title><idno type="ISSN">0901-5027</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animal model</term><term>Barrier</term><term>Biological effect</term><term>Biomaterial</term><term>Edentulousness</term><term>Experimental study</term><term>Guidance</term><term>Histology</term><term>Maxillary</term><term>Morphometry</term><term>Occlusion</term><term>Ossification</term><term>Quantitative analysis</term><term>Rabbit</term><term>Regeneration</term><term>Surgery</term><term>Technique</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Edentation</term><term>Ossification</term><term>Maxillaire</term><term>Guidage</term><term>Technique</term><term>Chirurgie</term><term>Biomatériau</term><term>Histologie</term><term>Morphométrie</term><term>Analyse quantitative</term><term>Barrière</term><term>Occlusion</term><term>Effet biologique</term><term>Etude expérimentale</term><term>Régénération</term><term>Modèle animal</term><term>Lapin</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Chirurgie</term><term>Biomatériau</term><term>Histologie</term><term>Analyse quantitative</term><term>Lapin</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The aims of this study were to evaluate the space-maintaining capacity of two biocompatible barrier materials and to assess the effect of barrier occlusiveness on the amount of regenerated bone. Defects were prepared in the edentulous area on both sides of the maxillas in 22 rabbits. The rabbits were divided into three groups. Gore-Tex® augmentation material (GTAM) (ePTFE)-barriers were placed to cover the experimental defects and compared with totally occlusive or perforated titanium foils and uncovered control defects respectively. After four weeks of healing, histological analyses and morphometrical measurements demonstrated that the amount of regenerated bone tissue was about the same underneath the collapsed GTAM-barriers as in the controls. The highest degree of regeneration was obtained in defects underneath the titanium foils, particularly if they were perforated, whether or not they were covered by GTAM-barriers. It was concluded that the space-maintaining properties of a barrier may be at least as important as barrier occlusiveness when regenerating bone defects.</div></front></TEI><affiliations><list><country><li>Suède</li></country><region><li>Götaland</li><li>Suède occidentale</li></region><settlement><li>Göteborg</li></settlement><orgName><li>Université de Göteborg</li></orgName></list><tree><country name="Suède"><region name="Götaland"><name sortKey="Lundgren, A K" sort="Lundgren, A K" uniqKey="Lundgren A" first="A. K." last="Lundgren">A. K. Lundgren</name></region><name sortKey="Lundgren, D" sort="Lundgren, D" uniqKey="Lundgren D" first="D." last="Lundgren">D. Lundgren</name><name sortKey="Lundgren, D" sort="Lundgren, D" uniqKey="Lundgren D" first="D." last="Lundgren">D. Lundgren</name><name sortKey="Sennerby, L" sort="Sennerby, L" uniqKey="Sennerby L" first="L." last="Sennerby">L. Sennerby</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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